Skip to Main Content
Treatment Cancer

Esophageal Cancer
Treatments

Surgery

Surgery is the most common treatment for esophageal cancer. Usually, the surgeon removes the tumor along with all or a portion of the esophagus, nearby lymph nodes and other tissue in the area. An operation to remove the esophagus is called an esophagectomy.

The surgeon connects the remaining healthy part of the esophagus to the stomach so that the patient is still able to swallow. The surgeon may also widen the opening between the stomach and the small intestine to allow stomach contents to pass more easily into the small intestine.

In some cases, we can remove the cancer using robotic surgery, a minimally invasive technique that can reduce recovery time and the risk of surgical complications.

Sometimes surgery is done after other treatment is finished.

Chemotherapy

Chemotherapy is the use of anticancer drugs to kill cancer cells. The anticancer drugs used to treat esophageal cancer travel throughout the body and are usually given by injection into a vein or intravenously.

Chemotherapy may be combined with radiation therapy as primary treatment, instead of surgery, or to shrink the tumor before surgery.

Laser Therapy

Laser therapy is the use of high-intensity light to destroy tumor cells. Laser therapy affects the cells only in the treated area. Laser therapy is used to destroy cancerous tissue and relieve a blockage in the esophagus when the cancer cannot be removed by surgery. The relief of a blockage can help to reduce symptoms, especially swallowing problems.

Photodynamic Therapy

Photodynamic therapy (PDT), a type of laser therapy, involves the use of drugs that are absorbed by cancer cells. When exposed to a special light, the drugs become active and destroy cancer cells. Your doctor may use PDT to relieve symptoms of esophageal cancer, such as difficulty swallowing.

Radiation Therapy

Radiation therapy, also called radiotherapy, involves the use of high-energy X-rays to kill cancer cells in the treated area only. The radiation may come from a machine outside the body – external radiation – or from radioactive materials placed in or near the tumor, called internal radiation.

A plastic tube may be inserted into the esophagus to keep it open during radiation therapy. This procedure is called intraluminal intubation and dilation.

Radiation therapy may be used alone or combined with chemotherapy as primary treatment instead of or before surgery, especially if the size or location of the tumor would make an operation difficult. Even if the tumor cannot be removed by surgery or destroyed entirely by radiation therapy, radiation therapy can often help relieve pain and make swallowing easier.

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.

Recommended reading

FAQ: Cancer Pathology Tissue Slides

Find frequently asked questions regarding cancer pathology tissue slides, such as how to obtain the slides and what to do with them once you do.

FAQ: Cancer Radiology Scans and Reports

Learn the difference between a radiology report and radiology films or scans as well as why your doctor may be requesting these scans and more.

Self-Care for Caregivers

Caregiver fatigue can be brought on by the physical and emotional demands of caring for a loved one with a serious illness. Learn tips to combat caregiver fatigue here.

Communicating with Your Doctor

The relationship with a doctor is a very personal one, built on communication and trust. In choosing a doctor, the "chemistry" between the two of you must work.

Coping with Chemotherapy

Each person experiences side effects from chemotherapy differently, and different chemotherapy drugs cause different side effects. Learn more here.

Delegation to Help with Fatigue

Fatigue caused by cancer treatment can make it difficult to accomplish even the smallest of tasks. Learn how task delegation can help with this fatigue.

Diet for Cancer Treatment Side Effects

Nausea is a common side effect of chemotherapy and radiation therapy. Find practical tips and suggested foods to help with nausea here.

Managing Your Treatment

Living with or caring for someone with cancer can be a full-time job. Here are some tips to reduce stress and help navigate the disease more effectively.

Nutrition and Coping with Cancer Symptoms

Side effects of cancer treatment may affect your eating pattern, requiring new ways to get the calories, protein and nutrients that you need. Learn more.

Questions to Ask Your Doctor

Your time with the doctor is limited, thus it's helpful to prepare for the visit in advance by prioritizing the questions that are important to you. Learn more.

Resources for End of Life

The UCSF Cancer Resource Center has a list of bereavement support groups, counselors, hospice and others dealing with end-of-life issues. Learn more.

Tips for Conserving Your Energy

Cancer and cancer therapy can be accompanied by feelings of extreme fatigue. To help you deal with this fatigue, follow these easy tips help conserve energy.

Using a Medical Calendar and Symptom Log

Take time at the end of each day or each week to reflect back on the symptoms you've had. You can use a calendar to track your symptoms. Learn more here.

Seeking care at UCSF Health

Expand Map

    Share